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Image Search Results
Journal: Neuron
Article Title: Neurodevelopmental patterns of early postnatal white matter maturation represent distinct underlying microstructure and histology.
doi: 10.1016/j.neuron.2022.09.020
Figure Lengend Snippet: Figure 6. Distinct cellular elements in the periventricular and intermediate NeWMaPs (A–D) Glial fibrillary acidic protein (GFAP) immu- nohistochemistry of the glial cells. Coronal sections through the frontoparietal junction (A), mid-parietal lobe (B), and posterior frontal lobe (C). (A–C) The dorsal frontoparietal periventricular NeWMaP-2 is demarcated from the surrounding parietal and periroladic intermediate white matter NeWMaPs (NeWMaP-6 and NeWMaP-9) and rostral frontal periventricular NeWMaP-8 by its intense GFAP immunoreactivity (marked by asterisk). (D) A distinct feature of the intermediate white matter compartment areas corresponding to NeWMaP-6 and NeWMaP-9 was the presence of radially oriented GFAP-reactive fibers, which likely represent remnants of the radial glial cells. (E) NeWMaP-8 is distinguished from the sur- rounding frontal white matter (e.g., NeWMaP-2) by Nissl staining (dashed arrow). A fine band of faint Nissl staining in the deep white matter was also represented by NeWMaP-8 (arrowheads). (F) Stain vector decomposition demonstrated doublecortin (DCX, a marker of young migrating neurons) expression in frontal periventricular white matter NeWMaP-8 (dashed arrow). See also Figure S6.
Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies GFAP Dako RRID:AB_10013382; Cat#
Techniques: Staining, Plasmid Preparation, Marker, Expressing